Allergic rhinitis in children with obesity: a modern view of the problem

Relevance. In recent decades, there has been an increase in a number of non-communicable chronic diseases and treated as a global health priority. There is an increase in the prevalence of allergic diseases, including allergic rhinitis (AR), and obesity in the pediatric population. In this regard, the study of AR in children with comorbid obesity is of particular interest. The aim of the review is to summarize current data on the immunological and clinical-epidemiological features of AR in children with comorbid obesity. Content. The review presents current information on the role of individual cytokines and adipokines in the development of chronic systemic inflammation in children with AR and obesity. An analysis of literature data on the significance of obesity as a possible risk factor for the development of AR in childhood is conducted. Clinical and epidemiological features are discussed, and individual studies are presented on some aspects of AR therapy in obese patients. Conclusions. The analysis showed that the currently available data on the relationship between AR and overweight/obesity in children are contradictory and require further research.