Case report highlights gastrointestinal disorders in patients with scleroderma, suggesting common complications.
Systemic sclerosis (SSc) is a systemic autoimmune disease in which gastrointestinal manifestations are a frequent complication. In as many as 90% of cases, there is intestinal involvement. The oesophagus and the anorectal tract are the regions most impacted. Digestion-related discomfort is most commonly caused by reflux, heartburn, and dysmotility. The development of faecal incontinence is significantly influenced by disordered anorectal function, which can happen early in the course of SSc. Oesophageal dysmotility, heartburn, dysphagia, nausea, vomiting, diarrhoea, constipation, bloating/distension, and faecal incontinence are among the symptoms of scleroderma that are frequently experienced. An endoscopy examination and manometry measurements are used to diagnose systemic sclerosis. Proton pump inhibitors, h2 receptor blockers, prokinetics, antibiotics, and laxatives are currently advised for the treatment of gastrointestinal disorders in SSc patients.
No takes yet. Share an insight, caveat, or question.
Sireesha et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: