Female fertility potential after coronavirus disease 2019 vaccinations

Background and aim During the ongoing coronavirus disease 2019 (COVID-19) pandemic, global mass vaccination campaigns utilizing newly developed vaccines have been implemented. However, apprehensions have arisen among recipients regarding potential adverse effects of vaccination on female reproductive health and fertility. We aimed to assess the association of COVID-19 vaccines with fertility among females trying to get pregnant. Patients and methods This prospective study, was performed on all fertile females who were administered two doses of COVID-19 vaccine in infertility clinic at Al-Azhar university hospitals Assiut and Qena general hospital during the period from February to December 2022. All females who did not received two dose of COVID-19 vaccine and suffered from any cause of infertility, regardless of receiving COVID-19 vaccine were excluded. Results Regarding Time to Pregnancy Occurrence, no statistically significant difference detected between the study groups ( P =0.998). Considering the gestational age, no statistically significant difference appeared between the study groups ( P =0.541). Conclusion Our study results provided that COVID-19 vaccines have no negative impacts on fertility. No statistically significant difference was detected among vaccinated individuals, our findings suggest the receiving the vaccine is unlikely to affect fertility. Further research may be carried out to confirm these results and provide additional insights.