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October 22, 2025Medicor Journal of Health Informatics and Health PolicyOpen Access

Vitamin B6, B9, and B12 Supplementation in Antipsychotic-Induced Akathisia: A Case Report and Comprehensive Review

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Authors

QSQuddus SalamTKTiwik KoesdiningsihMWMaya Widyantari

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Overview

Case report demonstrates B-vitamin supplementation improves akathisia in a patient with schizophrenia, suggesting nutritional support as a viable strategy.

Key Points

  • Following B12 supplementation and multimodal therapy, akathisia in the patient resolved and treatment adherence was restored.
  • The case report highlights the successful application of a therapeutic strategy combining B-vitamin supplementation and antipsychotic switching.
  • Assessment included folic acid, clobazam, and trihexyphenidyl alongside nutritional support focusing on dopaminergic pathways.
  • This approach underscores the significance of early akathisia recognition and prompts further trials for standardized treatment protocols.

Cite This Study

Salam et al. (2025) studied this question.

synapsesocial.com/papers/68f8a381c0c01e5ef8abdd3dhttps://doi.org/10.61978/medicor.v3i4.983
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