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Case report shows complete aneurysm occlusion in a patient with atrial fibrillation on oral anticoagulation, indicating eBFD as a viable alternative to traditional methods.
Wide neck bifurcation aneurysms are treated by intrasaccular implants, stent-assisted coiling, or flow diverters (FDs). The latter two options require long-term dual anti-platelet agents (DAPTs) and the former require access to the vulnerable aneurysm dome. 1 – 5 In patients requiring oral anticoagulation (OAC), an alternative treatment strategy would be advantageous to mitigate the foregoing risks. This report describes using a dedicated bifurcation FD, eCLIPs eBFD, to treat a basilar tip bifurcation aneurysm in a patient with atrial fibrillation requiring long-term OACs. The non-tubular eBFD aneurysm neck-bridging implant provides coil-retaining and flow diverting features and serves as a platform for endothelial growth. 6 , 7 It has shown flow velocity reduction at a bifurcation equivalent to a tubular FD at a sidewall. 8 In this case, eBFD, without coils, resulted in protracted intrasaccular stasis and resulted in complete aneurysm occlusion and neck remodeling within three months of discontinuation of dual anti-platelet therapy, without interrupting OAC.
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Mikkelsen et al. (2025) studied this question.
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