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October 21, 2025Future VirologyOpen Access

Antiretroviral therapy persistence following regimen switch or restart among treatment-experienced people with HIV

Joshua Cohen Benjamin Chastek Uche Mordi Mary J. Christoph Travis Lim Cassidy Trom Lisa Le

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Key Points

Persistence of antiretroviral therapy affects treatment success rates in HIV patients.
In a cohort of treatment-experienced individuals, ART persistence varied significantly post-regimen switch.
Observational analysis across multiple treatment centers in the US assessed ART continuity and outcomes in HIV.
These findings highlight the need for tailored interventions to improve ART adherence among diverse populations.

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Implication

Comparison of antiretroviral therapy persistence among treatment-experienced patients with HIV in the US indicates varying outcomes.

Abstract

Aims This study compared antiretroviral therapy (ART) persistence among people with HIV (PWH) in the United States.

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Cite This Study

Cohen et al. (2025) studied this question.

synapsesocial.com/papers/68f984011881b68f3b7ae5c6 https://doi.org/10.1080/17460794.2025.2574763

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1P-394. Antiretroviral therapy persistence following a change or restart in regimen among people with HIVRetrospective Study · 2026
2Antiretroviral Therapy Switching Among People with HIV in the United States is not Uncommon Despite Virologic Suppression: An OPERA Cohort StudyCohort Study · 2026
3Antiretroviral therapy persistence among treatment-experienced people with HIV and mental health disorders and/or substance use disorders in the USA (2017–2024): a retrospective cohort studyCohort Study · 2026
4Antiretroviral Treatment Switch Among Treatment-Experienced People with HIVRetrospective Study · 2026
5Prevalence of and Time to Suboptimal Treatment Patterns Among People with HIV on Antiretroviral Therapy in the United StatesCohort Study · 2026

Real-World Persistence After Starting Bictegravir- or Dolutegravir-Based Regimens Among Adults Aged ≥50 Years with HIV in the United States2026
P-390. Persistence and Adherence of People With HIV (PWH) and Mental Health Disorder Diagnosis Who Restart Antiretroviral Therapy (ART)2026
Clinical Characteristics, Healthcare Utilization, and Treatment Patterns Among People Living with HIV by Antiretroviral Therapy Use in the USA, 2021–20242026
Molecular chaperones in COVID-19 pathogenesis: viral life cycle, immunity and inflammationFuture Virology · 2026
The gut microbiota in HIV infection: dysbiosis, immune dysfunction, and implications for disease progression and managementFuture Virology · 2026

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