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October 27, 2025Biological and Clinical Sciences Research Journal

Comparison of Autologous Platelet-Rich Plasma (PRP)-Soaked Dressing vs. Saline-Soaked Dressing in the Healing of Diabetic Foot Ulcer

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Authors

HGHafiz Saad GulzarMIMuhammad Arslan IqbalMGMuhammad Azeem Gulzar

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Overview

Randomized controlled trial shows PRP dressing improves healing by 23% in diabetic foot ulcers, indicating better outcomes.

Key Points

  • Complete healing was achieved in 86.7% of the PRP group versus 64.0% for saline, highlighting superior efficacy.
  • The mean ulcer area reduced to 0.9 cm² with PRP and 2.7 cm² with saline after six weeks, indicating significant improvement.
  • Participants were adult patients with diabetic foot ulcers, treated over six weeks at a hospital in Pakistan.
  • PRP offers a biologically active alternative to saline dressings, suggesting potential for wider application in wound care.

Cite This Study

Gulzar et al. (2025) studied this question.

synapsesocial.com/papers/68ff87e2c8c50a61f2bdd02fhttps://doi.org/10.54112/bcsrj.v6i5.2032
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Comparative Study on the Effect of PRP in Healing Diabetic Foot Ulcers Compared to Standard Treatment in Diabetic Patients: A Randomized Clinical Trial Study2026 · 2 citations
  2. 2Efficacy of Platelet-Rich Plasma in the Treatment of Diabetic Foot Ulcer2024 · 6 citations
  3. 3Platelet-Rich Plasma for Wound Healing in Diabetic Patients2025
  4. 4Advancing Diabetic Wound Care with Platelet Rich Plasma: A Systematic Review of Mechanisms and Therapeutic Potential2025 · 1 citations
  5. 5Comparative efficacy of autologous platelet rich plasma and conventional dressing in the management of chronic ulcers2024 · 1 citations