[Guidelines for the management of cerebral venous thrombosis during pregnancy and the puerperium (2025 edition)].

Maternal and infant mortality rates are important indicators for evaluating the level of healthcare services in a country or a region. Due to physiological and internal environmental changes, women during pregnancy and the puerperium are at an increased risk of developing cerebral venous thrombosis (CVT). CVT occurring during pregnancy and the puerperium poses significant risks to both maternal and neonatal health. However, due to its hidden onset, non-specific clinical signs, and symptoms that overlap with normal perinatal changes, many clinicians lack adequate awareness and attention of it. To address this issue, the Expert Committee of the National Health Commission's Million Disability Reduction Project, together with the Cerebral Venous Disease Group of the Chinese Stroke Association and the Stroke Prevention and Control Professional Committee of the Chinese Preventive Medicine Association, convened leading experts from relevant fields across China to developed the "Guidelines for the management of cerebral venous thrombosis during pregnancy and the puerperium (2025 edition)" using the Delphi method on the basis of the latest domestic and international progress. These guidelines encompass eight aspects: epidemiology, pathogenesis and risk factors, clinical presentation, diagnosis and differential diagnosis, treatment, pregnancy and lactation, prevention strategies, and management of future pregnancies of CVT during pregnancy and postpartum period. A total of 49 recommendations are provided, aiming to establish a standardized and China-specific management framework for CVT during pregnancy and puerperium, and promote homogenized development of prevention and treatment capabilities across medical institutions at all levels.