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November 2, 2025The Bone & Joint Journal2 citations

The optimal centre of rotation for total hip arthroplasty in patients with unilateral Hartofilakidis type B developmental dysplasia of the hip

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BZBohan ZhangMLMingfeng LiHLHao Li

Key Points

  • Significant functional improvement was noted in total hip arthroplasty patients with DDH, especially those undergoing the mirroring reconstruction technique.
  • Harris Hip Scores improved significantly more in Group A compared to Group H, indicating superior outcomes associated with anatomical mirroring.
  • Cox regression analysis identified factors contributing to postoperative limping, contributing to the development of a useful nomogram for clinicians.
  • A power analysis confirmed the required sample size to detect a meaningful difference in gait recovery, enhancing study robustness.

Abstract

Aims The position of the centre of rotation (COR) for the best function and recovery of gait after total hip arthroplasty (THA) in patients with Hartofilakidis type B developmental dysplasia of the hip (DDH) remains controversial. This study aimed to compare the functional outcomes between two methods of reconstruction and quantify the optimal COR for the recovery of gait. Methods Out of 1,359 THAs which were identified, 223 patients (223 hips) with unilateral Hartofilakidis type B DDH and a normal contralateral hip who underwent anatomical mirroring reconstruction using autografts (Group A, 115 hips) or high hip centre (HHC) reconstruction (Group H, 108 hips) between January 2011 and June 2021 were reviewed. Functional and radiological results, including patient-reported outcome measures (PROMs), the height of the COR and offset, and recovery of gait, were compared between the groups. Factors associated with a limp were identified by Cox regression analysis and used to develop a nomogram. A power analysis indicated that 54 patients were required to detect a 25% difference in recovery of gait (α = 0.05, power = 0.80). Results During mean lengths of follow-up of 9.09 years (SD 3.21) and 8.62 years (SD 2.74) in Groups A and H, respectively, the Harris and Oxford Hip Scores significantly improved in both groups, with significantly better improvements in Group A than in Group H (both p < 0.001). Significantly more patients in Group A achieved recovery of gait than in Group H (103 (89.6%) vs 72 (66.7%); p < 0.001) at final follow-up. Early recovery of gait was significantly more likely in patients with smaller differences in COR height bilaterally (p < 0.001), younger patients (p = 0.021), and those who had not previously undergone a shelf acetabuloplasty (p < 0.001). The nomogram showed good performance (area under the receiver operating characteristic curve = 83.9%). Conclusion Significant functional improvement, with the COR placed < 1.18 cm above the normal contralateral hip, was achieved in both groups, but mirroring reconstruction provided earlier and better recovery of gait. We recommend that surgeons use this nomogram to assess the odds of there remaining a limp postoperatively before undertaking THA, in order to improve expectations and rehabilitation. Cite this article: Bone Joint J 2025;107-B(11):1171–1181.

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Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/6906a3a98b61f987b17a014ahttps://doi.org/10.1302/0301-620x.107b11.bjj-2025-0473.r1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Correction of limb-length inequality during total hip arthroplasty2001 · 230 citations
  2. 2Minimizing Preoperative and Postoperative Limping in Patients After Total Hip Arthroplasty2013 · 29 citations
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  4. 4Meta‐analysis of the Efficacy of the Anatomical Center and High Hip Center Techniques in the Treatment of Adult Developmental Dysplasia of the Hip2022 · 6 citations
  5. 5Functional and radiographical results of asymmetrically reconstructed total hip arthroplasty in patients with bilateral dysplastic arthritic hips with one hip Crowe II–III and the other Crowe IV: a retrospective cohort study2021 · 8 citations