The circadian variation of amino acids and melatonin in human milk and their potential sleep-wake regulation

Mengjun Cui; Jie Zhang; Renqiang Yu; Jianqiang Lai; Joe M. Regenstein; Peng Zhou

doi:10.1039/d5fo03369a

January 1, 2025Food & Function

The circadian variation of amino acids and melatonin in human milk and their potential sleep-wake regulation

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Key Points

Human milk contains bioactive components that vary throughout the day, enhancing sleep-wake regulation.
Melatonin and amino acids show diurnal variation, critical for establishing the biological clock in infants.
Assessment of amino acids and melatonin levels reveals their potential impact on sleep patterns.
These findings highlight the importance of nutritional timing for infant development and sleep health.

Implication

Observational analysis reveals diurnal variation of melatonin and amino acids in human milk, suggesting a role in sleep-wake regulation for infants.

Abstract

Human milk exhibits dynamic diurnal variations in bioactive components that is conducive to the consolidation of biological clock in early life, particularly in the establishment of sleep-wake cycle for infant....

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Cite This Study

Cui et al. (2025) studied this question.

synapsesocial.com/papers/690fdcdaf60c54d04ea38125 https://doi.org/10.1039/d5fo03369a

View at Publisher

Ask AI

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The circadian variation of amino acids and melatonin in human milk and their potential sleep-wake regulation

Key Points

Implication

Abstract

Discussion

Cite This Study

The circadian variation of amino acids and melatonin in human milk and their potential sleep-wake regulation

Key Points

Implication

Abstract

Discussion

Cite This Study

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