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May 29, 2020New England Journal of Medicine1,340 citationsOpen Access

Trastuzumab Deruxtecan in Previously Treated HER2-Positive Gastric Cancer

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KSKohei ShitaraUniversity of Padua
Yung‐Jue Bang
Yung‐Jue BangRutgers, The State University of New Jersey
SISatoru IwasaBrazilian Medical Association

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Abstract

Therapy with trastuzumab deruxtecan led to significant improvements in response and overall survival, as compared with standard therapies, among patients with HER2-positive gastric cancer. Myelosuppression and interstitial lung disease were the notable toxic effects. (Funded by Daiichi Sankyo; DESTINY-Gastric01 ClinicalTrials.gov number, NCT03329690.).

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Shitara et al. (2020) studied this question.

synapsesocial.com/papers/6914b9ff93f9c2bcff9a5c4fhttps://doi.org/10.1056/nejmoa2004413
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