Dupilumab Reduces Pruritus in Clinically Distinct Dermatologic Diseases: Data from Clinical Trials on Atopic Dermatitis, Prurigo Nodularis, and Chronic Spontaneous Urticaria

Q: What type of study is this?

This is a Pre-Registered Trial study.

Gil Yosipovitch; Brian S. Kim; John Y. Koo; Zhen Chen; Simmi Wiggins; Joseph Zahn; Philip Sugerman; El-Bdaoui Haddad; Sonya L Cyr

doi:10.1007/s13555-025-01596-8

November 22, 2025Dermatology and TherapyOpen Access

Dupilumab Reduces Pruritus in Clinically Distinct Dermatologic Diseases: Data from Clinical Trials on Atopic Dermatitis, Prurigo Nodularis, and Chronic Spontaneous Urticaria

View Full Paper

Ask AI

Bookmark

Share

Key Points

This research aims to examine the effects of dupilumab on pruritus across various dermatologic conditions.
Analysis of clinical trial data from several studies related to dupilumab.
Focus on atopic dermatitis, prurigo nodularis, and chronic spontaneous urticaria.
Data from ClinicalTrials.gov registrations (NCT02260986, NCT04183335/NCT04202679, NCT04180488)
Dupilumab significantly reduced pruritus in atopic dermatitis patients.
Reductions in pruritus were also observed in prurigo nodularis and chronic spontaneous urticaria.
These findings support the use of dupilumab across multiple dermatologic diseases.

No abstract yet

We only have this paper's title and publication details.

Read it at the source

Implication

Clinical trials show dupilumab reduces pruritus in atopic dermatitis, prurigo nodularis, and chronic spontaneous urticaria, indicating its effectiveness across distinct dermatologic diseases.

Abstract

ClinicalTrials.gov: NCT02260986, NCT04183335/NCT04202679, NCT04180488.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Yosipovitch et al. (2025) studied this question.

synapsesocial.com/papers/6924e3ddc0ce034ddc34e993 https://doi.org/10.1007/s13555-025-01596-8

View Full Paper

Ask AI

Bookmark

Share

Dupilumab Reduces Pruritus in Clinically Distinct Dermatologic Diseases: Data from Clinical Trials on Atopic Dermatitis, Prurigo Nodularis, and Chronic Spontaneous Urticaria

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Dupilumab Reduces Pruritus in Clinically Distinct Dermatologic Diseases: Data from Clinical Trials on Atopic Dermatitis, Prurigo Nodularis, and Chronic Spontaneous Urticaria

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Keep reading

More related papers

More from Dermatology and Therapy

Keep reading

More related papers

More from Dermatology and Therapy