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Genomic monitoring identifies sustained circulation of clade Ib MPXV in Burundi, indicating mutations and human transmission.
In summary, we identify sustained circulation of clade Ib MPXV in Burundi, most likely after several different introductions from the bordering province of South Kivu-DRC. The virus has acquired several additional APOBEC-3 mediated mutations, in line with reported evidence of ongoing human-to-human transmission.
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Nzoyikorera et al. (2025) studied this question.
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