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November 21, 2025Frontiers in Cardiovascular MedicineOpen Access

Machine learning-based screening of heart failure using the integrated features of electrocardiogram and phonocardiogram: a multicenter study in China

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Authors

JBJunjie BianKCKok Han CheeCLChengyu Liu

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Overview

A multicenter study shows machine learning algorithms improve heart failure detection using phonocardiogram and ECG data, suggesting clinical utility for early intervention.

Key Points

  • This study aims to validate an AI-based algorithm for early detection of heart failure using ECG and phonocardiogram data.
  • Multicenter study with 1,017 individuals divided into training and validating cohorts.
  • Used dimensionality reduction with the least absolute shrinkage and selection operator for model construction.
  • Evaluated multiple machine learning algorithms including logistic regression and random forest for screening heart failure.
  • 302 participants reported heart failure out of the total.
  • The CatBoost model achieved an area under the curve of 0.998, indicating high accuracy.
  • Sensitivity and specificity of the CatBoost model were both 0.989, demonstrating strong detection performance.

Cite This Study

Bian et al. (2025) studied this question.

synapsesocial.com/papers/6924e3f8c0ce034ddc34f441https://doi.org/10.3389/fcvm.2025.1613577
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