Analysis reveals elevated thrombogenic state in COPD during acute exacerbations, suggesting treatment may not prevent worsening.
Clot microstructural analysis demonstrates that COPD patients during acute exacerbation are more thrombogenic when compared to those with stable disease. This thrombogenic state is not aggravated with appropriate treatment on admission. Patients who died during exacerbations were in a significantly enhanced thrombogenic state when compared to those who survived as demonstrated by significantly elevated df.
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Pillai et al. (2025) studied this question.
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