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Imaging reveals liver stiffness correlations with therapy in Fontan patients, suggesting risks of hepatocellular carcinoma.
Fontan-associated liver disease (FALD) is a ubiquitous complication in patients with Fontan physiology. Optimal monitoring of FALD development typically starts with imaging. Liver stiffness values can help guide therapy and can act as a surrogate for disease severity. When nodules are present, they can be challenging. Looking for a lesion that behaves differently than other lesions is the best way to identify hepatocellular carcinoma.
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Betts et al. (2025) studied this question.
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