Observational study reveals waning immunity after Omicron infection, suggesting booster vaccinations are crucial for protection.
While Omicron infection induces robust short-term antibody responses, immunity wanes significantly within 6 months, and reinfection temporarily boosts antibody levels. The findings highlight the limited durability of natural and hybrid immunity and underscore the need for timely booster vaccinations to sustain protection, particularly in high-risk groups like HCWs.
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Wu et al. (2025) studied this question.
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