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lncrna mir100hg induces apoptosis and inflammation in nucleus pulposus cells, indicating its role in disc degeneration.
LncRNA MIR100HG targets miR-31-5p to inhibit NPCs proliferation and ECM anabolic metabolite expression, promote NPCs apoptosis and increased inflammatory levels, thereby inducing degenerative changes in NPCs.
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Tian et al. (2025) studied this question.
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