Systematic review shows intravesical instillations affect quality of life in non-muscle-invasive bladder cancer, suggesting need for patient-centered approaches.
Frequent intravesical instillations can significantly impair QoL, particularly among older patients. While emerging therapies and supportive strategies may help alleviate treatment burden, clinical decision-making must carefully balance QoL with oncologic outcomes. Future research should prioritize personalized approaches that integrate both clinical efficacy and patient-reported outcomes (PROs).
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Griebsch et al. (2025) studied this question.
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