Answers are grounded in this paper and cite their sources.
Plasma metabolic profiling reveals methotrexate non-response biomarkers in juvenile idiopathic arthritis, indicating gut microbiome's role.
These findings support plasma metabolomic differences associated with the response to MTX in JIA. The identification of hippurate, indoles, and other gut microbial-derived metabolites continues to draw attention to the potential relationship between the gut microbiome and MTX treatment response in JIA.
No takes yet. Share an insight, caveat, or question.
Kumar et al. (2025) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: