Case report highlights delayed meningioma regression in a transgender woman after hormone therapy cessation, suggesting surgical intervention may be necessary for severe symptoms.
CPA cessation alone may be an effective way to halt and even regress meningioma progression. However, its effect appears to be delayed, indicating that cessation alone is suboptimal in cases causing significant mass effect and symptomatology. In such cases, early surgical intervention should be considered.
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Goacher et al. (2025) studied this question.
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