The role of gemcitabine–docetaxel in the management of NMIBC: a scoping review of current status and future directions

Intravesical Gem/Doce has transitioned from an experimental salvage approach to a promising mainstream option in NMIBC management. Current evidence indicates that intravesical Gem/Doce can achieve durable disease control in a substantial proportion of patients with HR-NMIBC, offering a well-tolerated and cost-effective bladder-sparing strategy. While the absence of randomized trials means Gem/Doce is not yet a formal standard of care, the accumulating clinical experience and supportive outcomes have led to its inclusion in contemporary treatment algorithms.