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November 6, 2025Cardiovascular ResearchOpen Access

The Mediterranean diet and cardiovascular disease

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Authors

MBMaría Barbería-LatasaMMMiguel A. Martínez-González

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Overview

Systematic reviews and randomized controlled trials demonstrate Mediterranean diet's protective effects on cardiovascular disease, suggesting significant health benefits.

Key Points

  • This review aims to summarize the evidence regarding the Mediterranean diet and its relationship with cardiovascular disease.
  • Reviewed multiple large studies including randomized controlled trials and systematic reviews
  • Highlighted significant trials such as Lyon Diet-Heart Study, PREDIMED, and CORDIOPREV
  • Applied metabolomics techniques to assess adherence to the Mediterranean diet
  • Consistent findings show Mediterranean diet reduces risk of cardiovascular disease
  • Emphasizes benefits of plant-based foods and healthy fats, particularly extra virgin olive oil
  • Controversy regarding the inclusion of moderate alcohol consumption, evaluated in ongoing UNATI trial

Cite This Study

Barbería-Latasa et al. (2025) studied this question.

synapsesocial.com/papers/69253a39c0ce034ddc357e23https://doi.org/10.1093/cvr/cvaf218
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