Cross-sectional analysis correlates executive function indicators with education levels in adults with cirrhosis and healthy older adults, indicating ReacStick's broad applicability.
Objective Neuropsychological tests of executive function often rely on reading, writing, and/or calculation, introducing educational bias. ReacStick uses a rapid go/no-go paradigm (within a 390 millisecond window) to assess attention, processing speed, inhibition, and working memory without requiring proficiency in reading, writing, or calcuation. Design Secondary analyses using cross-sectional data examined the impact of years of education on Trails B, a gold-standard measure of executive function, and ReacStick parameters in healthy older adults (n = 139) and adults with hepatic cirrhosis (n = 118). Results Fewer years of education correlated with longer Trails B completion times (r = -0.214; p < 0.001) and accounted for 5.3% of Trails B variance when controlling for age, gender, and clinical group (cirrhosis vs. older) as covariates. In contrast, years of education showed no significant relationship with ReacStick accuracy parameters (On, Off, and All Accuracy). Similar results were obtained when years of education was dichotomized (≤ 12 vs. > 12 years). Conclusion ReacStick offers a quantifiable test of executive function with limited education bias, supporting its use in diverse population, including those with limited educational attainment or non-native English speakers.
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Lane et al. (2025) studied this question.
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