Preliminary study reports 94.4% tumor control and 91.7% survival rates in patients with large meningiomas, suggesting CyberKnife is a promising option.
BACKGROUND This preliminary study evaluates the efficacy and safety of CyberKnife hypofractionated radiosurgery for large-volume meningiomas (≥10cc). METHODS We retrospectively analyzed 18 patients treated between 2010 and 2020 at Gyeongsang National University Hospital. RESULTS Results showed a local tumor control rate of 94.4% and a 5-year overall survival rate of 91.7%. Symptomatic peritumoral edema occurred in 61.1% of patients, with most cases managed conservatively, and 16.7% requiring surgical intervention. CONCLUSION These findings suggest that CyberKnife radiosurgery is a viable option for selected patients with large meningiomas, meriting further research with larger cohorts and extended follow-ups.
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Kyeong-O Go (2025) studied this question.
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