Perspective: Radiotherapy and Body Composition: Unmet Needs in Low- and Middle-Income Countries

Radiotherapy (RT) plays a vital role in cancer treatment, yet its effects on patients' nutritional status can precipitate muscle loss, with significant implications for treatment tolerance and outcomes. Evidence from high-income countries increasingly links radiation induced muscle loss to adverse clinical outcomes. In contrast, low- and middle-income countries (LMICs) face a stark evidence gap, despite the heightened vulnerability of cancer patients in these settings due to delayed diagnosis, limited access to care, and high rates of co-morbidities. This paper highlights the critical gaps in nutritional care for RT patients in LMICs.