Cohort study reveals higher risk of protein-losing enteropathy in patients with right ventricular morphology, suggesting implications for treatment strategies.
PLE remains a serious complication following Fontan with notable mortality. Patients with right ventricular morphology of the systemic ventricle had a higher risk of PLE. Previous pulmonary venous congestion was common when PLE was diagnosed early after Fontan. Catheter-based interventions were frequently used to optimize hemodynamics; lymphatic interventions are likely to become more common. In therapy-resistant patients heart transplantation remains an option.
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Dolk et al. (2025) studied this question.
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