Case-control study reveals lipid profiles correlate with cognitive impairment in multiple sclerosis, suggesting physical activity may influence outcomes.
Key Points
The research aims to explore the relationship between lipid profiles and cognitive function in patients with multiple sclerosis.
Case-control study with 71 patients with multiple sclerosis and 71 healthy controls.
Lipid biomarkers such as cholesterol, triglycerides, and lipoproteins were analyzed from blood samples.
Cognitive function was assessed using the Symbol Digit Modalities Test and BICAMS, while disability was measured with EDSS.
Cognitive impairment was associated with lipid biomarkers in multiple sclerosis patients.
Higher triglyceride levels correlated positively with disease progression and cognitive impairment.
A negative correlation was found between the Symbol Digit Modalities Test scores and total cholesterol and LDL-C.