An asymmetric Beckmann sequence enables the synthesis of enantioenriched 5–7-membered lactams from prochiral and meso cycloalkanones. The selectivity originates from an enantioselective condensation followed by a stereospecific rearrangement.
No takes yet. Share an insight, caveat, or question.
Hammes et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: