Absorption characteristics and in vivo behavior of astaxanthin isomers: insights from the administration of highly purified (all- E )-, (9 Z )-, and (13 Z )-astaxanthin in male mice

Antara Ghosh; Yoshiharu Sawada; Kentaro Takahama; Yasuhiro Nishida; Masaki Honda

doi:10.1039/d5ra06060e

January 1, 2025RSC AdvancesOpen Access

Absorption characteristics and in vivo behavior of astaxanthin isomers: insights from the administration of highly purified (all- E )-, (9 Z )-, and (13 Z )-astaxanthin in male mice

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Key Points

The study aims to evaluate the absorption characteristics and in vivo behavior of different astaxanthin isomers in mice.
Administered highly purified all-E, 9Z, and 13Z astaxanthin to male mice
Examined bioavailability, systemic retention, and hepatic accumulation of each isomer
(13Z)-Astaxanthin showed significantly higher bioavailability than (all-E)- and (9Z)-isomers
Higher systemic retention and hepatic accumulation observed for (13Z)-isomer
Findings suggest (13Z)-isomer has promising nutraceutical applications.

Implication

Administration of astaxanthin isomers reveals (13Z)-astaxanthin has higher bioavailability in male mice, suggesting nutraceutical potential.

Abstract

(13 Z )-Astaxanthin exhibits significantly higher bioavailability, systemic retention, and hepatic accumulation than the (all- E )- and (9 Z )-isomers, highlighting its potential for nutraceutical applications.

Discussion

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Cite This Study

Ghosh et al. (2025) studied this question.

synapsesocial.com/papers/6925572cc0ce034ddc35a694 https://doi.org/10.1039/d5ra06060e

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Absorption characteristics and in vivo behavior of astaxanthin isomers: insights from the administration of highly purified (all- E )-, (9 Z )-, and (13 Z )-astaxanthin in male mice

Key Points

Implication

Abstract

Discussion

Cite This Study

Absorption characteristics and in vivo behavior of astaxanthin isomers: insights from the administration of highly purified (all- E )-, (9 Z )-, and (13 Z )-astaxanthin in male mice

Key Points

Implication

Abstract

Discussion

Cite This Study

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