Green initiatives for the synthesis of polyamide monomers: precision fermentation using engineered Corynebacterium glutamicum and extraction of purified 5-aminovaleric acid (5AVA) and putrescine

Keerthi Sasikumar; Volker F. Wendisch; K. Madhavan Nampoothiri

doi:10.1039/d5su00799b

January 1, 2025RSC SustainabilityOpen Access

Green initiatives for the synthesis of polyamide monomers: precision fermentation using engineered Corynebacterium glutamicum and extraction of purified 5-aminovaleric acid (5AVA) and putrescine

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Key Points

Improved extraction methods yielded higher recovery rates of 5-aminovaleric acid and putrescine, supporting biopolyamide production.
Noteworthy advancements in microbial production were observed using engineered Corynebacterium glutamicum under optimized bioprocess conditions.
Observational analysis focused on precision fermentation techniques and their impact on biomass efficiency and product yield.
Highlights the significance of green alternatives to petroleum-derived pathways for sustainable resource management.

Implication

Precision fermentation enhances recovery of 5-aminovaleric acid and putrescine, suggesting sustainable biopolymer production.

Abstract

Schematic representation of microbial production, bioprocess optimization and recovery of 5-aminovaleric acid (5AVA) and putrescine as green alternative to petroleum-based synthesis for bio-polyamide production.

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Cite This Study

Sasikumar et al. (2025) studied this question.

synapsesocial.com/papers/69255731c0ce034ddc35aa8f https://doi.org/10.1039/d5su00799b

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Green initiatives for the synthesis of polyamide monomers: precision fermentation using engineered Corynebacterium glutamicum and extraction of purified 5-aminovaleric acid (5AVA) and putrescine

Key Points

Implication

Abstract

Discussion

Cite This Study

Green initiatives for the synthesis of polyamide monomers: precision fermentation using engineered Corynebacterium glutamicum and extraction of purified 5-aminovaleric acid (5AVA) and putrescine

Key Points

Implication

Abstract

Discussion

Cite This Study

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