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Dietary fiber interventions improve metabolic pathways in mice with PCOS, indicating gut microbiota as therapeutic targets.
RS2 and AX alleviated PCOS phenotypes by enriching Ligilactobacillus, increasing SCFA production, and activating hepatic AMPK signaling. These findings highlight gut microbiota modulation and SCFA-driven metabolic pathways as therapeutic targets for PCOS. This study provides mechanistic insights into dietary fiber interventions for endocrine disorders.
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Liang et al. (2025) studied this question.
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