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January 1, 2025New Journal of Chemistry

Fluorescent Monitoring of STING with Coumarin-based Chemigenetic Probe

Xuekun Zhang Yu Jiang Ying Wang Yaxi Li Haozhou Tang Andong Shao Jianming Ni

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Key Points

Monitoring STING activity offers insights into cellular processes and their significance in biotechnology and medicine.
Key findings underscore the relationship between STING and cell fate decision in cellular homeostasis, indicating potential therapeutic avenues.
Analysis of protein condensates through fluorescent probes highlights their role in maintaining cellular functions and responding to stimuli.
Insights gained may enable advancements in biomolecular research and applications in treatments related to cell signaling.

Implication

Fluorescent monitoring of STING reveals effects on cell fate decision in cells, suggesting important implications for research.

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Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/6928f12ea65b730b9ea7a681 https://doi.org/10.1039/d5nj03804a

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