Meigs’ Syndrome in [18F]FDG and [18F]FAPI-42 Imaging

Follicular membrane cell tumor/fibroadenoma is a tumor originating from the ovarian stromal cells, typically producing estrogen that may cause symptoms such as postmenopausal bleeding or endometrial hyperplasia. This tumor is usually benign, but rare malignant forms exist, appearing as a solid ovarian mass on imaging and are considered for surgical removal (oophorectomy or cystectomy) if symptomatic. When a patient has ovarian fibroids, pleural effusion, and ascites, a diagnosis of Meigs syndrome needs to be considered. In this case, we report a patient with frequent urination, urgency, and nocturia who underwent [ 18 F]FDG and [ 18 F]FAPI-42 PET/CT scan to look for a lesion, which was finally detected in the left adnexa by the latter.