Analysis shows multiplicity and risk influence patient outcomes in intracranial aneurysms, highlighting exposure's role.
MIAs were associated with higher patient-time rupture and SAH-specific mortality and greater lesion-level instability, but not with an independent per-aneurysm rupture hazard. The excess patient-level risk is largely explained by exposure (multiplicity); a symmetry-related effect remains plausible but unconfirmed. Larger, prospectively harmonised datasets are needed.
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Roj et al. (2025) studied this question.
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