Analysis shows mcr-1 gene transmission in livestock and poultry leads to human infections, suggesting polypeptide resistance dynamics.
Key Points
Bacterial infections caused by mcr-1 strains circulated undetected for over three decades in China, leading to significant public health concerns.
Seventy mcr-1-positive strains were analyzed from hospital surveillance data alongside 671 strains from the NCBI database.
The study employs genetic dynamics to reveal how the mcr-1 gene disseminates across diverse bacterial hosts in agricultural settings.
This research highlights the implications of agricultural practices on the emergence of antibiotic resistance, indicating the need for effective monitoring.