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Observational analysis revealed enhanced therapeutic efficacy in radionuclide therapy, indicating further studies on bystander effects may improve cancer treatment.
This study elucidates the complex interplay of direct and bystander effects in targeted radionuclide therapy, demonstrating that the therapeutic efficacy and cellular response depend on the specific radionuclide and its energy profile. The findings emphasize the need for further exploration of RIBBEs to optimize radionuclide-based cancer therapies to enhance their clinical efficacy.
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Sharma et al. (2025) studied this question.
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