December 2, 2025Open Access

Repeatability and reproducibility of hemodynamic measurements by intracranial 4D Flow MRI: a multi‑vendor and multi‑software cross‑over comparison study

Key Points

Measurements showed significant variation in flow rates based on software methods used, emphasizing the need for standardization.
The analysis indicated that multiple software platforms may lead to inconsistencies in hemodynamic measurements.
Cross-over comparison involving different MRI vendors demonstrated the impact of software on observational reliability and validity.
Ensuring consistency in multi-center clinical studies may require employing a single software approach for post-processing.

Abstract

Scanning protocols by different vendors appear to result in smaller variations in flow rate compared to using different post-processing software methods. It is recommended to employ single post-processing software or conduct software calibration when using multiple software platforms to ensure consistency in multi-center clinical studies.

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Cite This Study

Luo et al. (Fri,) studied this question.

synapsesocial.com/papers/692e3d846c9b3ab28c18732f https://doi.org/https://doi.org/10.1186/s12880-025-02039-8

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