Findings demonstrate impaired autophagy increases ferroptosis risk in diabetes, suggesting therapeutic strategies targeting kidney injury may help.
These findings demonstrate that impaired autophagy and inactivated AMPK heighten susceptibility to ferroptosis in DKD, suggesting that therapeutic strategies targeting autophagy and AMPK activation may reduce ferroptosis-associated kidney injury in individuals with diabetes.
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Matsui et al. (2025) studied this question.
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