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December 4, 2025Journal of Proteome ResearchOpen Access

Exploring Biomarkers in Type 2 Diabetes Mellitus versus Normoglycemia Identified through High-Throughput Proteomics: A Systematic Review and Meta-Analysis

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Authors

GTGuillermo L. Taboada

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Overview

Systematic review and meta-analysis identify protein biomarkers linked to lipid metabolism in individuals with type 2 diabetes, suggesting avenues for further exploration.

Key Points

  • Metabolic disturbances linked to biomarkers are identified in individuals with type 2 diabetes and normoglycemia.
  • Meta-analysis highlights key proteins in lipid metabolism and immune response, showing strong interconnectivity.
  • Proteomic profiles analyze data across 27 studies with significant variation in outcomes yet noted consistency in several markers.
  • Findings support the use of biomarkers for understanding type 2 diabetes, with calls for further validation and exploration.

Cite This Study

Guillermo L. Taboada (2025) studied this question.

synapsesocial.com/papers/6930dc6bea1aef094cca1f28https://doi.org/10.1021/acs.jproteome.5c00773
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