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December 4, 2025Annals of Medicine2 citationsOpen Access

Cellular characteristics of the immune microenvironment of colorectal cancer and progress in immunotherapy research

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LXLei XiaXCXinran CaoXWXueliang Wu

Key Points

  • Immunotherapy targeting may reshape management in colorectal cancer, enhancing therapeutic effectiveness.
  • Colorectal cancer management benefits from advancements in immunotherapy strategies and immune microenvironment targeting.
  • Observational analysis on immune dynamics highlights the importance of metabolic interactions in cancer therapy.
  • These findings indicate significant potential for personalized, multi-target immunotherapy in clinical paradigms.

Abstract

Special consideration is directed toward the translational value of targeting immune-metabolic interactions and spatial dynamics within the TME. Ultimately, this work synthesizes current knowledge and outlines forward-looking strategies to advance personalized, multi-target immunotherapy, with the potential to reshape clinical paradigms in CRC management.

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Cite This Study

Xia et al. (2025) studied this question.

synapsesocial.com/papers/6930dc78ea1aef094cca2217https://doi.org/10.1080/07853890.2025.2591308
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