Evaluation of Platelet Parameters in Relation to Aspartate Aminotransferase to Platelet Ratio Index and Fibrosis-4 Scores among Non-alcoholic Fatty Liver Disease Patients and Healthy Controls: An Exploratory Study
Observational analysis assessed mean platelet volume and APRI scores in NAFLD patients, suggesting potential non-invasive tools for detecting liver fibrosis.
Key Points
Platelet parameters showed no significant intergroup differences between NAFLD patients and controls, indicating diagnostic limits of these indices.
Mean platelet volume was assessed alongside Fibrosis-4 and APRI scores, finding correlations between these metrics.
Cross-sectional analysis on 30 NAFLD patients and 30 healthy controls was conducted at a tertiary healthcare center.
Findings highlight the need for larger studies to further explore the diagnostic relevance of these scores. Once stratified by fibrosis, results may vary.