December 4, 2025ACS Nano

Membrane-Targeting Poly(Amino Acids) with a Phage-Like Action Process for Antifungal Therapy

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Analysis shows improved antifungal activity with PArg20 in fungal infections, indicating potential to reduce resistance.

Antifungal therapy reduced the time for fungal eradication from over 2 hours to just 10 minutes.
PArg20 demonstrated significant biocompatibility while triggering mitochondrial dysfunction and oxidative stress.
Membrane-targeting poly(amino acid) therapy utilized electrostatic interactions for effective delivery and action.
Supporting antifungal strategies may enable better management of invasive fungal infections and curb resistance.

Zhao et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark