Fine-Tuning J-Aggregation via Steric Hindrance for High-Efficiency NIR-II Bioimaging and Photothermal Therapy

Hong Zhang; Kun Li

doi:10.1039/d5mh01966d

December 2, 2025Materials Horizons

Fine-Tuning J-Aggregation via Steric Hindrance for High-Efficiency NIR-II Bioimaging and Photothermal Therapy

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Key Points

Improved bioimaging efficacy has been indicated, leveraging specific J-aggregates for optimized results.
Significant enhancements in near-infrared imaging are linked to fine-tuning J-aggregates with steric hindrance.
Assessment of molecular scaffolds using steric hindrance highlights potential in imaging techniques.
Innovative strategies may enable advancements in photothermal therapy, revealing their impact on therapeutic practices.

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Implication

Innovative approach improves high-efficiency bioimaging in NIR-II, suggesting J-aggregates may enhance photothermal therapy.

Abstract

J-aggregates emitting in the second near-infrared window (NIR-II) show significant potential for in vivo imaging. However, progress has been hindered by the limited diversity of molecular scaffolds and the challenge...

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Zhang et al. (2025) studied this question.

synapsesocial.com/papers/6930e8bdea1aef094cca3221 https://doi.org/10.1039/d5mh01966d

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Fine-Tuning J-Aggregation via Steric Hindrance for High-Efficiency NIR-II Bioimaging and Photothermal Therapy

Key Points

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Implication

Abstract

Discussion

Cite This Study

Fine-Tuning J-Aggregation via Steric Hindrance for High-Efficiency NIR-II Bioimaging and Photothermal Therapy

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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