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December 1, 2025

The Utility of CSF Biomarkers in Diagnosing Alzheimer's Disease: A Thai Cohort Study.

Witsarut Nanthasi Chatchawan Rattanabannakit Natthamon Wongkom Pathitta Dujada Atthapon-Raksthaput Sunisa Chaichanettee Paphawadee Phoyoo Leatchai Wachirutmanggur Seong Soo A. An Vorapun Senanarong

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Key Points

Accurate diagnosis of Alzheimer's may enhance with specific cerebrospinal fluid biomarkers in clinical settings.
CSF cutoffs for differentiating Alzheimer's from non-AD dementia were established, indicating significant clinical relevance.
Data-driven approach utilized in this observational analysis provides a valid methodology for diagnosing dementia.
Integration of clinical and biological profiles is pivotal for improving dementia diagnostic accuracy and patient care.

Implication

Observational analysis established CSF cutoffs for Alzheimer's and dementia in a Thai cohort, indicating improved diagnosis accuracy.

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Cite This Study

Nanthasi et al. (2025) studied this question.

synapsesocial.com/papers/6930e8cdea1aef094cca3869 https://doi.org/10.1159/000548539

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Biological markers of Alzheimer's disease in cerebrospinal fluid: clinical and laboratory comparisons2024 · 17 citations
2Usefulness of Cerebrospinal Fluid Alzheimer's disease biomarkers in older patients: Evidence from a national multicenter prospective studyCohort Study · 2025 · 4 citations
3Cross-Validation of Neurodegeneration Biomarkers in Blood and CSF for Dementia ClassificationOriginal Research · 2026
4Cerebrospinal Fluid Biomarkers of Alzheimer DiseaseReview · 2025 · 1 citations
5Using Cerebrospinal Fluid Biomarkers To Enhance Diagnostic Testing For Alzheimer's Disease In A Tertiary Memory Service2024

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