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December 4, 20250 citations

Squamous Cell Carcinoma of the Oral Cavity: Molecular Pathways and Therapeutic Approaches

Recent knowledge on squamous cell carcinoma of the oral cavity: Contributing factors, underlying molecular pathways, and current attitudes in the therapeutic approaches.

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Authors

RAReza Mahmoudi AnzabiADAmir Hossein DavodpourSGSoroush Ghodratizadeh

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Overview

This overview highlights risk factors and emerging therapeutic strategies to improve outcomes in oral cavity squamous cell carcinoma, suggesting further research is needed.

Key Points

  • Tumor progression linked with factors including tobacco use and viral infections, emphasizing prevention measures.
  • Essential risk factors and molecular pathways identified, potentially guiding personalized treatment strategies.
  • Combination therapies using metformin and cisplatin show promise in enhancing chemotherapy sensitivity and targeting tumor growth.
  • Continued exploration of novel therapies is crucial for improving survival and quality of life in OCSCC patients.

Cite This Study

Anzabi et al. (2025) studied this question.

synapsesocial.com/papers/6930e8cdea1aef094cca387fhttps://doi.org/10.22088/ijmcm.bums.14.3.928
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Comprehensive Review of Risk Factors, Diagnosis, and Treatment Options for Oral Squamous Cell Carcinoma2025 · 8 citations
  2. 2Unravelling molecular mechanism of oral squamous cell carcinoma and genetic landscape: an insight into disease complexity, available therapies, and future considerations2025
  3. 3Genetic and molecular insights in oral squamous cell carcinoma therapy - Advancing the horizon2024 · 1 citations
  4. 4From Environmental Risk to Cancer Stemness: Epigenetic Regulation in Oral Squamous Cell Carcinoma2026
  5. 5Exploring Metabolic and Immunological Biomarkers for Oral Squamous Cell Carcinoma: Potential Targets for Precision Therapy2025 · 5 citations