December 4, 2025BiomedicinesOpen Access

miRNA-155-3p and miRNA-3196 as Potential Biomarkers in Liquid Biopsies of Non-Small Cell Lung Cancer Patients

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Authors

DADaniela Alexandre JPJoana Polido SVSalete Valente

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Implication

This research identifies miRNA-155-3p and miRNA-3196 as potential biomarkers for non-small cell lung cancer, suggesting their role in diagnosis and therapy monitoring.

Key Points

Circulating levels of miRNA-155-3p and miRNA-3196 were assessed for prognostic value in non-small cell lung cancer.
The area under the curve for miR-155-3p was 0.881, indicating strong diagnostic potential based on liquid biopsy.
Assessment involved RT-qPCR of PBMCs from 136 NSCLC patients and 64 healthy controls to quantify microRNA expression.
Findings indicate that combined use of these biomarkers could improve diagnostic specificity for NSCLC.

Cite This Study

Alexandre et al. (2025) studied this question.

synapsesocial.com/papers/6930e8dbea1aef094cca3cbb https://doi.org/10.3390/biomedicines13122946

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Implication

This research identifies miRNA-155-3p and miRNA-3196 as potential biomarkers for non-small cell lung cancer, suggesting their role in diagnosis and therapy monitoring.

miRNA-155-3p and miRNA-3196 as Potential Biomarkers in Liquid Biopsies of Non-Small Cell Lung Cancer Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

miRNA-155-3p and miRNA-3196 as Potential Biomarkers in Liquid Biopsies of Non-Small Cell Lung Cancer Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

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