What type of study is this?

This is a Human Clinical Trial study (also classified as: RCT).

December 5, 2025BMC AnesthesiologyOpen Access

Comparison of anesthetic effects of spinal anesthesia at L5-S1 and L3-4 under real-time ultrasound guidance in total knee arthroplasty: a single center randomized controlled trial

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Anesthetic effects are compared between spinal anesthesia at L5-S1 and L3-4 in total knee arthroplasty.
Key findings reveal differences in anesthetic outcomes, emphasizing the importance of injection site.
Randomized controlled trial evaluates effects under ultrasound guidance, supporting precision in administration.
Highlighting the role of ultrasound guidance, results may inform better practices in knee arthroplasty.

Randomized controlled trial compares anesthetic effects of spinal anesthesia at L5-S1 and L3-4, indicating ultrasound guidance may improve outcomes.

This trial was registered on July 21, 2025 at the Chinese Clinical Trial center (No. ChiCTR2500106275). Retrospectively registered.

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Li et al. (2025) studied this question.

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Randomized controlled trial compares anesthetic effects of spinal anesthesia at L5-S1 and L3-4, indicating ultrasound guidance may improve outcomes.

This trial was registered on July 21, 2025 at the Chinese Clinical Trial center (No. ChiCTR2500106275). Retrospectively registered.