Metagenomic analysis shows improved prediction of colonization in very preterm infants, suggesting new prevention strategies.
Our study demonstrates that metagenomic quantification of pathobionts such as S. aureus in intestinal samples provides a stronger predictor of colonization than culture. Future prevention strategies should focus on promoting S. aureus colonization resistance through microbiome-informed approaches.
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Knoll et al. (2025) studied this question.
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