Harnessing biological insights to accelerate drug discovery against ESKAPE pathogens

Tashi Palmo; Vishwani Jamwal; DIKSHA KUMARI; Kuljit Singh

doi:10.1039/d5md00358j

December 3, 2025RSC Medicinal Chemistry

Harnessing biological insights to accelerate drug discovery against ESKAPE pathogens

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Key Points

Drug discovery is crucial for tackling antimicrobial resistance and multidrug-resistant bacteria, leading to enhanced treatment options.
Global health crisis is driven by the rise in drug-resistant infections, especially among ESKAPE pathogens.
Observational analysis highlights the urgent need for biological insights to accelerate drug development.
Implications suggest that understanding resistance mechanisms may enable effective strategies against resistant pathogens.

Implication

This study shows drug discovery progress against multidrug-resistant bacteria, indicating an essential step in addressing antimicrobial resistance.

Abstract

The escalating global health crisis of antimicrobial resistance (AMR) is driven by the increasing prevalence of drug-resistant bacterial infections, particularly among the ESKAPE pathogens. These multidrug-resistant bacteria pose a significant...

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Cite This Study

Palmo et al. (2025) studied this question.

synapsesocial.com/papers/693231308e51979591dce794 https://doi.org/10.1039/d5md00358j

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Harnessing biological insights to accelerate drug discovery against ESKAPE pathogens

Key Points

Implication

Abstract

Discussion

Cite This Study

Harnessing biological insights to accelerate drug discovery against ESKAPE pathogens

Key Points

Implication

Abstract

Discussion

Cite This Study

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